Orlistat (Xenical) 120mg


Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytriciniHowever, due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.

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Orlistat is a drug designed to treat obesity.

It is marketed as a prescription drug under the trade name Xenical by Roche in most countries, and is sold over-the-counter as Alli by GlaxoSmithKline in the United Kingdom and the United States.

Its primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake.

It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet.

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This medication is used with a doctor-approved exercise, behavior change, and reduced-calorie diet program to help you lose weight.

It is used by certain overweight people, such as those who are obese or have weight-related medical problems. Taking orlistat can also help keep you from gaining back weight you have lost.

Losing weight and keeping it off can lessen the many health risks that come with obesity, including heart disease, diabetes, high blood pressure, and a shorter life.

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Dietary fats need to be broken down into smaller pieces before the body can absorb them. Orlistat works by blocking the enzyme that breaks down fats in your diet.

This undigested fatthen passes out of your body in your bowel movement. Orlistat does not block the absorption of calories from sugar and other non-fat foods, so you still need to restrict your total intake of calories.

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How does Orlistat work for weight loss?

Orlistat works by binding to the enzymes in the body to prevent the absorption of fat.

On average, Orlistat will work on around a quarter to one-third of the fat you eat. Instead of this fat being absorbed, it passes through your gut. For people with high-fat diets, this can result in oily stools.

Is Orlistat effective in weight loss?

Xenical has been clinically proven to help you on your weight loss  when used in conjunction with diet and exercise. It can help you achieve 50% more weight loss than you would get from dieting alone.

For every 2lb you manage to lose through a healthy life style, Orlistat can boost your weight loss by another 1lb. Orlistat helps reduce fat absorption by 25-33%.

In trials, patients on Orlistat are twice as likely to lose over 10% of their body weight over the course of a year, in comparison to someone using diet alone. It should be noted, when taking Orlistat, diet and exercise are still key to achieving best results.

Who can use Orlistat?

Orlistat is indicated in people with a BMI over 30, or in people who have a BMI over 28, with another weight-related condition, such as diabetes or high blood pressure.

How does Xenical work?

Xenical, or Orlistat, in its generic form, works by reducing the amount of fat absorbed from your diet; it is not an appetite suppressant. When fat enters the body, it is broken down by enzymes called lipases, so that the body can digest it. Xenical (Orlistat) attaches itself to the enzymes in the body so that they cannot break down the fat

The undigested fat is then passed through your digestive system with no unwanted effects on your heart rate or sleeping pattern.

Orlistat has been tested in hundreds of clinical studies and has proven to be very safe, yet very efficient. Xenical (Orlistat) should only be used by those who are medically obese; those with a BMI of 30 or more or a BMI of 28 or more in those with other risk factors such as diabetes or hypertension.

What is the difference between Alli/ Xenical and Orlistat?

Alli is an over the counter version of Orlistat, which is half the strength of the prescribed version. Alli contains 60mg of Orlistat, compared to 120mg in Xenical and generic prescription Orlistat.

What are the side effects of Xenical/ Orlistat?

The side effects are usually mild and don’t affect everybody, but could include: Headaches Low blood sugar Stomach pain / trapped wind Increase in regularity of bowel movements Oily or loose stools Oily discharge

How should i take Xenical

One 120mg capsule can be taken up to three times per day – just before, with a meal or up to an hour afterwards. Do not take more than three capsules a day Each capsule should be swallowed whole, with water.

A multivitamin should be taken a couple of hours after taking Xenical, or at bedtime to ensure your body retains its necessary levels of vitamins A, D, E and K.

Xenical can lower the absorption of these fat soluble vitamins.

It should not be taken with a meal that does not contain any fat and if a meal is missed then Xenical should not be taken.

You should see a reduction of around 5% of your body weight within the first twelve weeks; if you have not seen any results in this time, Xenical may not be the weight loss aid for you.

Xenical should only be used until you reach a BMI of 28.

Your results can be greatly enhanced by following a calorie controlled diet and taking regular exercise.

It should be taken with a nutritionally balanced, low calorie diet that has no more than about 30% of calories from fat.

Taking Xenical with any meal high in fat (more than 30% fat) may make the potential side effects worse.


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